Cellular Protection
DMSO is well-known for protecting cells from many otherwise deadly stressors. For example, it prevents freezing damage to cells, which made modern cryopreservation (cryomedicine) possible, and extensive research shows that this protective effect works across nearly every type of tissue (along with repeatedly saving human fingers and animal ears or limbs1,2,3 from being lost to frostbite). As the cells of the nervous system are particularly sensitive to injury (and often unable to heal from it), DMSO’s protective qualities are particularly useful for it. Core mechanisms of protection include:

•Reducing oxidative stress1,2,3,4 and neutralizing harmful free radicals1,2,3 (e.g., those caused by radiation like hydroxyl) through scavenging charged ions (e.g., H+) and forming protective DMSO radicals (along with decreasing lipofuscin formation in human glial cells, reducing the cumulative oxidative damage that drives cellular aging). In hippocampal slices DMSO also counteracted this oxidative stress,1,2 and in cerebellar granule neurons, this prevented oxidative stress-induced apoptosis and cell death by reducing early mitochondrial impairment and DNA fragmentation1,2 (with similar benefits also being seen when DMSO was combined with CDK and G9a inhibitors1,2). Trace amounts of DMSO also protect plants from ozone gas injury and counteract reactive hypochlorous acid, superoxide, and hydrogen peroxide (while simultaneously working synergistically with oxidative therapies and not impairing neutrophil viability).

Note: if any of you have profound DMSO stories you would like to share, please share them here and consider reaching out to Rebecca so she can document them.

The extensive evidence behind DMSO’s ability to treat ‘incurable’ neurological diseases — and how to use it

LINK TO DETAILS: https://open.substack.com/pub/amidwesterndoctor/p/how-dmso-heals-the-brain-and-transforms?r=1dbkwf&utm_medium=ios